Structurally and functionally distinct early antibody responses predict COVID-19 disease trajectory and mRNA vaccine response

A damaging inflammatory response is strongly implicated in the pathogenesis of severe COVID-19 but mechanisms contributing to this response are unclear. In two prospective cohorts, early non-neutralizing, afucosylated, anti-SARS-CoV-2 IgG predicted progression from mild, to more severe COVID-19. In...

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Detaylı Bibliyografya
Yayımlandı:bioRxiv
Asıl Yazarlar: Chakraborty, Saborni, Gonzalez, Joseph C., Sievers, Benjamin L., Mallajosyula, Vamsee, Chakraborty, Srijoni, Dubey, Megha, Ashraf, Usama, Cheng, Bowie Yik-Ling, Kathale, Nimish, Tran, Kim Quyen Thi, Scallan, Courtney, Sinnott, Aanika, Cassidy, Arianna, Chen, Steven T., Gelbart, Terri, Gao, Fei, Golan, Yarden, Ji, Xuhuai, Kim-Schulze, Seunghee, Prahl, Mary, Gaw, Stephanie L., Gnjatic, Sacha, Marron, Thomas U., Merad, Miriam, Arunachalam, Prabhu S., Boyd, Scott D., Davis, Mark M., Holubar, Marisa, Khosla, Chaitan, Maecker, Holden T., Maldonado, Yvonne, Mellins, Elizabeth D., Nadeau, Kari C., Pulendran, Bali, Singh, Upinder, Subramanian, Aruna, Utz, Paul J., Sherwood, Robert, Zhang, Sheng, Jagannathan, Prasanna, Tan, Gene S., Wang, Taia T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168384/
https://ncbi.nlm.nih.gov/pubmed/34075376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.05.25.445649
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