HGG-34. A DNA DAMAGE REPAIR SIGNATURE IN PRIMARY AND RECURRENT PEDIATRIC HIGH-GRADE GLIOMAS: PROGNOSTIC AND THERAPEUTIC VALUE

Pediatric high-grade gliomas (pHGGs), including diffuse intrinsic pontine gliomas (DIPGs), despite their low incidence, are the leading cause of mortality in pediatric neuro-oncology. Frequently, pHGGs, harboring mainly histone mutations, are or become resistant to standard therapies like irradiatio...

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Entz-Werle, Natacha, Poidevin, Laetitia, Nazarov, Petr, Lhermitte, Benoit, Chenard, Marie Pierre, Poch, Olivier, Dontenwill, Monique, Van Dyck, Eric
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
Schlagworte:
High Grade Gliomas
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168130/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noab090.098
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