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EMBR-17. DE-INTENSIFICATION OF RADIOTHERAPY IN RIGOROUSLY DEFINED LOW-RISK WNT-SUBGROUP MEDULLOBLASTOMA IS ASSOCIATED WITH UNACCEPTABLY HIGH RISK OF NEURAXIAL FAILURE: RESULTS FROM THE PROSPECTIVE FOR-WNT STUDY

BACKGROUND: Medulloblastoma is a heterogenous disease comprising four molecular subgroups (WNT, SHH, Group 3, and Group 4) with varying outcomes. Excellent long-term survival (>90%) has prompted de-intensification of therapy in WNT-subgroup medulloblastoma globally. FOR-WNT is one such prospectiv...

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Gupta, Tejpal, Pervez, Shizan, Dasgupta, Archya, Chatterjee, Abhishek, Krishnatry, Rahul, GodaSastri, Jayant, Prasad, Maya, Chinnaswamy, Girish, Epari, Sridhar, Sahay, Ayushi, Shirsat, Neelam, Shetty, Prakash, Moiyadi, Aliasgar, Shaikh, Farnaz, Bano, Nazia, Jalali, Rakesh
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168092/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noab090.035
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