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A robust unsupervised machine-learning method to quantify the morphological heterogeneity of cells and nuclei

Cell morphology encodes essential information on many underlying biological processes. It is commonly used by clinicians and researchers in the study, diagnosis, prognosis, and treatment of human diseases. Quantification of cell morphology has seen tremendous advances in recent years. However, effec...

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Bibliographic Details
Published in:Nat Protoc
Main Authors: Phillip, Jude M., Han, Kyu-Sang, Chen, Wei-Chiang, Wirtz, Denis, Wu, Pei-Hsun
Format: Artigo
Language:Inglês
Published: 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167883/
https://ncbi.nlm.nih.gov/pubmed/33424024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-020-00432-x
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