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Alpha-fetoprotein response at different time-points is associated with efficacy of nivolumab monotherapy for unresectable hepatocellular carcinoma

Nivolumab monotherapy has a modest objective response rate (ORR) in hepatocellular carcinoma (HCC). To overcome the lack of biomarkers that predict delayed alpha-fetoprotein (AFP) response beyond 4 weeks, we applied a novel 50-10 rule of AFP response for unresectable HCC patients under nivolumab mon...

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Pubblicato in:Am J Cancer Res
Autori principali: Teng, Wei, Lin, Chen-Chun, Ho, Ming-Mo, Lui, Kar-Wai, Wang, Sheng-Fu, Hsu, Chao-Wei, Lin, Shi-Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167682/
https://ncbi.nlm.nih.gov/pubmed/34094688
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