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Laryngeal squamous cell carcinoma cell lines show high tolerance for siRNA-mediated CDK1 knockdown

Alterations of the cell cycle checkpoints lead to uncontrolled cell growth and result in tumorigenesis. One of the genes essential for cell proliferation and cell cycle regulation is CDK1. This makes it a potential target in cancer therapy. In our previous study we have shown upregulation of this ge...

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Detalles Bibliográficos
Publicado en:Am J Cancer Res
Main Authors: Bednarek, Kinga, Kostrzewska-Poczekaj, Magdalena, Ustaszewski, Adam, Janiszewska, Joanna, Kiwerska, Katarzyna, Paczkowska, Julia, Grenman, Reidar, Giefing, Maciej, Jarmuz-Szymczak, Malgorzata
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167681/
https://ncbi.nlm.nih.gov/pubmed/34094670
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