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Modulators of neuroinflammation have a beneficial effect in a Lafora disease mouse model

Lafora disease (LD; OMIM#274780) is a fatal rare neurodegenerative disorder characterized by generalized epileptic seizures and the presence of polyglucosan inclusions (PGs), called Lafora bodies (LBs), typically in the brain. LD is caused by mutations in two genes EPM2A or EPM2B, which encode respe...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Mollá, Belén, Heredia, Miguel, Sanz, Pascual
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167455/
https://ncbi.nlm.nih.gov/pubmed/33447969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-021-02285-1
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