Adiponectin Attenuates Lipopolysaccharide-induced Apoptosis by Regulating the Cx43/PI3K/AKT Pathway

Cardiomyocyte apoptosis is a crucial factor leading to myocardial dysfunction. Adiponectin (APN) has a cardiomyocyte-protective impact. Studies have shown that the connexin43 (Cx43) and phosphatidylinositol-3-kinase (PI3K)/protein kinase B (AKT) signaling pathways play an important role in the heart...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Liu, Luqian, Yan, Meijuan, Yang, Rui, Qin, Xuqing, Chen, Ling, Li, Li, Si, Junqiang, Li, Xinzhi, Ma, Ketao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167433/
https://ncbi.nlm.nih.gov/pubmed/34084134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.644225
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