UGT1A1 mutation association with increased bilirubin levels and severity of unconjugated hyperbilirubinemia in ABO incompatible newborns of China

BACKGROUND: Neonatal hyperbilirubinemia causing jaundice is common in East Asian population. Uridine diphosphate glucuronosyltransferase isoenzyme (UGT1A1) glucuronidates bilirubin and converts the toxic form of bilirubin to its nontoxic form. METHOD: A retrospective study was conducted to review cl...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Pediatr
Auteurs principaux: Yang, Hui, Lin, Fen, Chen, Zi-kai, Zhang, Lin, Xu, Jia-Xin, Wu, Yong-Hao, Gu, Jing-Ying, Ma, Yu-Bin, Li, Jian-Dong, Yang, Li-Ye
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167307/
https://ncbi.nlm.nih.gov/pubmed/34074250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12887-021-02726-9
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