Strategies to tackle RAS-mutated metastatic colorectal cancer

The RAS oncogene is among the most commonly mutated in cancer. RAS mutations are identified in about half of patients diagnosed with metastatic colorectal cancer (mCRC), conferring poor prognosis and lack of response to anti-epidermal growth factor receptor (EGFR) antibodies. In the last decades, se...

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Vydáno v:ESMO Open
Hlavní autoři: Patelli, G., Tosi, F., Amatu, A., Mauri, G., Curaba, A., Patanè, D.A., Pani, A., Scaglione, F., Siena, S., Sartore-Bianchi, A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167159/
https://ncbi.nlm.nih.gov/pubmed/34044286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.esmoop.2021.100156
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