Chlorine inhalation induces acute chest syndrome in humanized sickle cell mouse model and ameliorated by postexposure hemopexin

Triggering factors of Acute Chest Syndrome (ACS) is a leading cause of death in patients with Sickle Cell Disease (SCD) and targeted therapies are limited. Chlorine (Cl(2)) inhalation happens frequently, but its role as a potential trigger of ACS has not been determined. In this study, we hypothesiz...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Alishlash, Ammar Saadoon, Sapkota, Muna, Ahmad, Israr, Maclin, Kelsey, Ahmed, Noor A., Molyvdas, Adam, Doran, Stephen, Albert, Carolyn J., Aggarwal, Saurabh, Ford, David A., Ambalavanan, Namasivayam, Jilling, Tamas, Matalon, Sadis
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167148/
https://ncbi.nlm.nih.gov/pubmed/34044323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.102009
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