MMP8 increases tongue carcinoma cell–cell adhesion and diminishes migration via cleavage of anti-adhesive FXYD5

Matrix metalloproteinases (MMPs) modify bioactive factors via selective processing or degradation resulting in tumour-promoting or tumour-suppressive effects, such as those by MMP8 in various cancers. We mapped the substrates of MMP8 to elucidate its previously shown tumour-protective role in oral t...

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Gepubliceerd in:Oncogenesis
Hoofdauteurs: Juurikka, K., Dufour, A., Pehkonen, K., Mainoli, B., Campioni Rodrigues, P., Solis, N., Klein, T., Nyberg, P., Overall, C. M., Salo, T., Åström, P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2021
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167110/
https://ncbi.nlm.nih.gov/pubmed/34059618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-021-00334-x
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