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Transient incubation of cultured hippocampal neurons in the absence of magnesium induces rhythmic and synchronized epileptiform-like activity

Cell culture models are important tools to study epileptogenesis mechanisms. The aim of this work was to characterize the spontaneous and synchronized rhythmic activity developed by cultured hippocampal neurons after transient incubation in zero Mg(2+) to model Status Epilepticus. Cultured hippocamp...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mele, Miranda, Vieira, Ricardo, Correia, Bárbara, De Luca, Pasqualino, Duarte, Filipe V., Pinheiro, Paulo S., Duarte, Carlos B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167095/
https://ncbi.nlm.nih.gov/pubmed/34059735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90486-y
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