Ferroptotic pores induce Ca(2+) fluxes and ESCRT-III activation to modulate cell death kinetics

Ferroptosis is an iron-dependent form of regulated necrosis associated with lipid peroxidation. Despite its key role in the inflammatory outcome of ferroptosis, little is known about the molecular events leading to the disruption of the plasma membrane during this type of cell death. Here we show th...

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Udgivet i:Cell Death Differ
Main Authors: Pedrera, Lohans, Espiritu, Rafael A., Ros, Uris, Weber, Josephine, Schmitt, Anja, Stroh, Jenny, Hailfinger, Stephan, von Karstedt, Silvia, García-Sáez, Ana J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167089/
https://ncbi.nlm.nih.gov/pubmed/33335287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00691-x
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