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Nano-Sized Hydroxyapatite Induces Apoptosis and Osteogenic Differentiation of Vascular Smooth Muscle Cells via JNK/c-JUN Pathway

PURPOSE: The deposition of hydroxyapatite (HAp) crystals plays an important role in the development of vascular calcification (VC). This study aimed to demonstrate the effects of nanosized HAp (nHAp) on vascular smooth muscle cells (VSMCs) and VC progression. METHODS: Transmission electron microscop...

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Dettagli Bibliografici
Pubblicato in:Int J Nanomedicine
Autori principali: Liu, Qi, Xiang, Pingping, Chen, Mingyao, Luo, Yi, Zhao, Yun, Zhu, Jinyun, Jing, Wangwei, Yu, Hong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8166281/
https://ncbi.nlm.nih.gov/pubmed/34079254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S303714
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