Structural basis for p50RhoGAP BCH domain–mediated regulation of Rho inactivation

Spatiotemporal regulation of signaling cascades is crucial for various biological pathways, under the control of a range of scaffolding proteins. The BNIP-2 and Cdc42GAP Homology (BCH) domain is a highly conserved module that targets small GTPases and their regulators. Proteins bearing BCH domains a...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Chichili, Vishnu Priyanka Reddy, Chew, Ti Weng, Shankar, Srihari, Er, Shi Yin, Chin, Cheen Fei, Jobichen, Chacko, Qiurong Pan, Catherine, Zhou, Yiting, Yeong, Foong May, Low, Boon Chuan, Sivaraman, J.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8166187/
https://ncbi.nlm.nih.gov/pubmed/34006635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2014242118
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