Pharmacological inhibition of MDA-9/Syntenin blocks breast cancer metastasis through suppression of IL-1β

Melanoma differentiation associated gene-9 (MDA-9), Syntenin-1, or syndecan binding protein is a differentially regulated prometastatic gene with elevated expression in advanced stages of melanoma. MDA-9/Syntenin expression positively associates with advanced disease stage in multiple histologically...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Pradhan, Anjan K., Maji, Santanu, Bhoopathi, Praveen, Talukdar, Sarmistha, Mannangatti, Padmanabhan, Guo, Chunqing, Wang, Xiang-Yang, Cartagena, Lorraine Colon, Idowu, Michael, Landry, Joseph W., Sarkar, Devanand, Emdad, Luni, Cavenee, Webster K., Das, Swadesh K., Fisher, Paul B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8166168/
https://ncbi.nlm.nih.gov/pubmed/34016751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2103180118
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