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Impact of an alpha helix and a cysteine–cysteine disulfide bond on the resistance of bacterial adhesion pili to stress

Escherichia coli express adhesion pili that mediate attachment to host cell surfaces and are exposed to body fluids in the urinary and gastrointestinal tracts. Pilin subunits are organized into helical polymers, with a tip adhesin for specific host binding. Pili can elastically unwind when exposed t...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Baker, Joseph L., Dahlberg, Tobias, Bullitt, Esther, Andersson, Magnus
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8166124/
https://ncbi.nlm.nih.gov/pubmed/34011607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2023595118
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