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On the evolution of chaperones and cochaperones and the expansion of proteomes across the Tree of Life

Across the Tree of Life (ToL), the complexity of proteomes varies widely. Our systematic analysis depicts that from the simplest archaea to mammals, the total number of proteins per proteome expanded ∼200-fold. Individual proteins also became larger, and multidomain proteins expanded ∼50-fold. Apart...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Rebeaud, Mathieu E., Mallik, Saurav, Goloubinoff, Pierre, Tawfik, Dan S.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8166112/
https://ncbi.nlm.nih.gov/pubmed/34001607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2020885118
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