Microevolution in the pansecondary metabolome of Aspergillus flavus and its potential macroevolutionary implications for filamentous fungi

Fungi produce a wealth of pharmacologically bioactive secondary metabolites (SMs) from biosynthetic gene clusters (BGCs). It is common practice for drug discovery efforts to treat species’ secondary metabolomes as being well represented by a single or a small number of representative genomes. Howeve...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Drott, Milton T., Rush, Tomás A., Satterlee, Tatum R., Giannone, Richard J., Abraham, Paul E., Greco, Claudio, Venkatesh, Nandhitha, Skerker, Jeffrey M., Glass, N. Louise, Labbé, Jesse L., Milgroom, Michael G., Keller, Nancy P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8166093/
https://ncbi.nlm.nih.gov/pubmed/34016748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2021683118
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