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Brain HIV-1 latently-infected reservoirs targeted by the suicide gene strategy

Reducing the pool of HIV-1 reservoirs in patients is a must to achieve functional cure. The most prominent HIV-1 cell reservoirs are resting CD4 + T cells and brain derived microglial cells. Infected microglial cells are believed to be the source of peripheral tissues reseedings and the emergence of...

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Detalhes bibliográficos
Publicado no:Virol J
Main Authors: Saeb, Sepideh, Ravanshad, Mehrdad, Pourkarim, Mahmoud Reza, Daouad, Fadoua, Baesi, Kazem, Rohr, Olivier, Wallet, Clémentine, Schwartz, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8166011/
https://ncbi.nlm.nih.gov/pubmed/34059075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-021-01584-2
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