Safety and efficacy of umbilical cord-derived Wharton’s jelly compared to hyaluronic acid and saline for knee osteoarthritis: study protocol for a randomized, controlled, single-blind, multi-center trial

BACKGROUND: Osteoarthritis (OA) is the most common joint disorder in the United States of America (USA) with a fast-rising prevalence. Current treatment modalities are limited, and total knee replacement surgeries have shown disadvantages, especially for grade II/III OA. The interest in the use of b...

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Bibliographic Details
Published in:J Orthop Surg Res
Main Authors: Gupta, Ashim, Maffulli, Nicola, Rodriguez, Hugo C., Carson, Eric W., Bascharon, Randa A., Delfino, Kristin, Levy, Howard J., El-Amin, Saadiq F.
Format: Artigo
Language:Inglês
Published: BioMed Central 2021
Subjects:
Study Protocol
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8165766/
https://ncbi.nlm.nih.gov/pubmed/34059080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-021-02475-6
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