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Intepirdine as adjunctive therapy to donepezil for mild‐to‐moderate Alzheimer's disease: A randomized, placebo‐controlled, phase 3 clinical trial (MINDSET)

INTRODUCTION: A previous phase 2b study supported the use of the 5‐HT6 receptor antagonist intepirdine as adjunctive therapy to donepezil for Alzheimer's disease (AD) dementia. A phase 3 study, MINDSET, was performed to test this hypothesis. METHODS: MINDSET was a global, double‐blind, randomiz...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement (N Y)
Main Authors: Lang, Frederick M., Mo, Yi, Sabbagh, Marwan, Solomon, Paul, Boada, Merce, Jones, Roy W., Frisoni, Giovanni B., Grimmer, Timo, Dubois, Bruno, Harnett, Mark, Friedhoff, Sarah R., Coslett, Shari, Cummings, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8165732/
https://ncbi.nlm.nih.gov/pubmed/34095437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/trc2.12136
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