Sensing Enzyme Activation Heat Capacity at the Single-Molecule Level Using Gold-Nanorod-Based Optical Whispering Gallery Modes

[Image: see text] Here, we report a label-free gold nanoparticle-based single-molecule optical platform to study the immobilization, activity, and thermodynamics of single enzymes. The sensor uses plasmonic gold nanoparticles coupled to optical whispering gallery modes (WGMs) to probe enzyme conform...

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發表在:ACS Appl Nano Mater
Main Authors: Subramanian, Sivaraman, Jones, Hannah B.L., Frustaci, Simona, Winter, Samuel, van der Kamp, Marc W., Arcus, Vickery L., Pudney, Christopher R., Vollmer, Frank
格式: Artigo
語言:Inglês
出版: American Chemical Society 2021
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8165693/
https://ncbi.nlm.nih.gov/pubmed/34085031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsanm.1c00176
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