Mitomycin C Inhibits Esophageal Fibrosis by Regulating Cell Apoptosis and Autophagy via lncRNA-ATB and miR-200b

Benign esophageal strictures (BESs) frequently results from esophageal fibrosis. The transformation of fibroblasts into fibrocyte is an important cause of fibrosis. The treatment of fibrosis is challenging. Some previous studies have indicated the antifibrotic effect of mitomycin C (MMC). However, t...

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Bibliographische Detailangaben
Veröffentlicht in:Front Mol Biosci
Hauptverfasser: Zhang, Yin, Wang, Qinge, Xu, Yuping, Sun, Jing, Ding, Yanbo, Wang, Li, Chen, Bingfang, Sun, Kewen, Chen, Jianping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Molecular Biosciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8165251/
https://ncbi.nlm.nih.gov/pubmed/34079820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.675757
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