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Total Glucosides of Paeony Inhibited Autophagy and Improved Acute Kidney Injury Induced by Ischemia-Reperfusion via the lncRNA TUG1/miR-29a/PTEN Axis

OBJECTIVE: Total glucosides of paeony (TGP) has been proven to affect anti-inflammatory, immunomodulatory and hypoxia tolerance. This study investigates the effect of TGP on autophagy in acute kidney injury (AKI) induced by ischemia-reperfusion (I/R). METHODS: Rat model of AKI induced by I/R was est...

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Vydáno v:Drug Des Devel Ther
Hlavní autoři: Chang, Xiaoyan, Zhang, Pei, Xu, Xing-Xin, Pang, Bo
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8164873/
https://ncbi.nlm.nih.gov/pubmed/34079224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S286606
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