The role of FoxP3+ regulatory T cells and IDO+ immune and tumor cells in malignant melanoma – an immunohistochemical study

BACKGROUND: FoxP3+ Regulatory T cells (Tregs) and indoleamine-2,3-dioxygenase (IDO) participate in the formation of an immunosuppressive tumor microenvironment (TME) in malignant cutaneous melanoma (CM). Recent studies have reported that IDO expression correlates with poor prognosis and greater Bres...

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Detalles Bibliográficos
Publicado en:BMC Cancer
Main Authors: Salmi, Satu, Lin, Anton, Hirschovits-Gerz, Benjamin, Valkonen, Mari, Aaltonen, Niina, Sironen, Reijo, Siiskonen, Hanna, Pasonen-Seppänen, Sanna
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2021
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8164759/
https://ncbi.nlm.nih.gov/pubmed/34051744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-021-08385-4
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