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Corticosteroid enhances epithelial barrier function in intestinal organoids derived from patients with Crohn’s disease

ABSTRACT: Corticosteroids (CS), first-line therapeutics for Crohn’s disease (CD) with moderate or severe disease activity, were found to restore intestinal permeability in CD patients, whereas the underlying molecular events are still largely unknown. This study aimed to investigate the effect and m...

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書目詳細資料
發表在:J Mol Med (Berl)
Main Authors: Xu, Pan, Elizalde, Montserrat, Masclee, Ad, Pierik, Marieke, Jonkers, Daisy
格式: Artigo
語言:Inglês
出版: Springer Berlin Heidelberg 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8164603/
https://ncbi.nlm.nih.gov/pubmed/33575854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-021-02045-7
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