Corticosteroid enhances epithelial barrier function in intestinal organoids derived from patients with Crohn’s disease

ABSTRACT: Corticosteroids (CS), first-line therapeutics for Crohn’s disease (CD) with moderate or severe disease activity, were found to restore intestinal permeability in CD patients, whereas the underlying molecular events are still largely unknown. This study aimed to investigate the effect and m...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Mol Med (Berl)
Prif Awduron: Xu, Pan, Elizalde, Montserrat, Masclee, Ad, Pierik, Marieke, Jonkers, Daisy
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Berlin Heidelberg 2021
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8164603/
https://ncbi.nlm.nih.gov/pubmed/33575854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-021-02045-7
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