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Corticosteroid enhances epithelial barrier function in intestinal organoids derived from patients with Crohn’s disease

ABSTRACT: Corticosteroids (CS), first-line therapeutics for Crohn’s disease (CD) with moderate or severe disease activity, were found to restore intestinal permeability in CD patients, whereas the underlying molecular events are still largely unknown. This study aimed to investigate the effect and m...

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Detalhes bibliográficos
Publicado no:J Mol Med (Berl)
Principais autores: Xu, Pan, Elizalde, Montserrat, Masclee, Ad, Pierik, Marieke, Jonkers, Daisy
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8164603/
https://ncbi.nlm.nih.gov/pubmed/33575854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-021-02045-7
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