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Correcting QUEST Magnetic Resonance Imaging–Sensitive Free Radical Production in the Outer Retina In Vivo Does Not Correct Reduced Visual Performance in 24-Month-Old C57BL/6J Mice

PURPOSE: To test the hypothesis that acutely correcting a sustained presence of outer retina free radicals measured in vivo in 24-month-old mice corrects their reduced visual performance. METHODS: Male C57BL/6J mice two and 24 months old were noninvasively evaluated for unremitted production of para...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Berkowitz, Bruce A., Podolsky, Robert H., Childers, Karen Lins, Roberts, Robin, Schneider, Michael, Graffice, Emma, Sinan, Kenan, Berri, Ali, Harp, Lamis
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8164372/
https://ncbi.nlm.nih.gov/pubmed/34036313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.62.6.24
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