PRL-1 overexpressed placenta-derived mesenchymal stem cells suppress adipogenesis in Graves’ ophthalmopathy through SREBP2/HMGCR pathway

BACKGROUND: Graves’ ophthalmopathy (GO) is a disorder, in which orbital connective tissues get in inflammation and increase in volume. Stimulants such as thyroid-stimulating hormone (TSH), insulin-like growth factor 1(IGF-1), IL-1, interferon γ, and platelet-derived growth factor cause differentiati...

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Vydáno v:Stem Cell Res Ther
Hlavní autoři: Park, Mira, Kim, Jae Yeon, Kang, Jun Mo, Lee, Hey Jin, Banga, Jasvinder Paul, Kim, Gi Jin, Lew, Helen
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8164285/
https://ncbi.nlm.nih.gov/pubmed/34051850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02337-2
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