3D-printed nerve guidance conduits multi-functionalized with canine multipotent mesenchymal stromal cells promote neuroregeneration after sciatic nerve injury in rats

BACKGROUND: Nerve injuries are debilitating, leading to long-term motor deficits. Remyelination and axonal growth are supported and enhanced by growth factor and cytokines. Combination of nerve guidance conduits (NGCs) with adipose-tissue-derived multipotent mesenchymal stromal cells (AdMSCs) has be...

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Udgivet i:Stem Cell Res Ther
Main Authors: Rodríguez-Sánchez, Diego Noé, Pinto, Giovana Boff Araujo, Cartarozzi, Luciana Politti, de Oliveira, Alexandre Leite Rodrigues, Bovolato, Ana Livia Carvalho, de Carvalho, Marcio, da Silva, Jorge Vicente Lopes, Dernowsek, Janaina de Andréa, Golim, Marjorie, Barraviera, Benedito, Ferreira, Rui Seabra, Deffune, Elenice, Bertanha, Mathues, Amorim, Rogério Martins
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8164252/
https://ncbi.nlm.nih.gov/pubmed/34051869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02315-8
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