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Phosphorylation of protein kinase Cδ Tyr311 positively regulates thromboxane generation in platelets

Platelets are key mediators of physiological hemostasis and pathological thrombosis, whose function must be carefully balanced by signaling downstream of receptors such as protease-activated receptor (PAR)4. Protein kinase C (PKC) is known to regulate various aspects of platelet function. For instan...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Kostyak, John C., Mauri, Benjamin, Patel, Akruti, Dangelmaier, Carol, Reddy, Haritha, Kunapuli, Satya P.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8164046/
https://ncbi.nlm.nih.gov/pubmed/33932405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100720
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