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HLA DR Genome Editing with TALENs in Human iPSCs Produced Immune-Tolerant Dendritic Cells

Although human induced pluripotent stem cells (iPSCs) can serve as a universal cell source for regenerative medicine, the use of iPSCs in clinical applications is limited by prohibitive costs and prolonged generation time. Moreover, allogeneic iPSC transplantation requires preclusion of mismatches b...

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Bibliographic Details
Published in:Stem Cells Int
Main Authors: Kwon, Yoo-Wook, Ahn, Hyo-Suk, Lee, Jin-Woo, Yang, Han-Mo, Cho, Hyun-Jai, Kim, Seok Joong, Lee, Shin-Hyae, Yang, Heung-Mo, Jang, Hyun-Duk, Kim, Sung Joo, Kim, Hyo-Soo
Format: Artigo
Language:Inglês
Published: Hindawi 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8163544/
https://ncbi.nlm.nih.gov/pubmed/34093711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/8873383
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