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A ratiometric fluorescent probe for real-time monitoring of intracellular glutathione fluctuations in response to cisplatin

Real-time imaging of fluctuations in intracellular glutathione (GSH) concentrations is critical to understanding the mechanism of GSH-related cisplatin-resistance. Here, we describe a ratiometric fluorescence probe based on a reversible Michael addition reaction of GSH with the vinyl-functionalized...

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Publicat a:Chem Sci
Autors principals: Liu, Hanzhuang, Song, Wenting, Zhang, Shuren, Chan, Kin Shing, Guo, Zijian, Shen, Zhen
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society of Chemistry 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8163343/
https://ncbi.nlm.nih.gov/pubmed/34123110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc02889d
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