Ethnic differences in excretion of butadiene–DNA adducts by current smokers

1,3-Butadiene (BD) is a known human carcinogen used in the synthetic polymer industry and also found in cigarette smoke, automobile exhaust and wood burning smoke. BD is metabolically activated by cytochrome P450 monooxygenases (CYP) 2E1 and 2A6 to 3,4-epoxy-1-butene (EB), which can be detoxified by...

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Dades bibliogràfiques
Publicat a:Carcinogenesis
Autors principals: Jokipii Krueger, Caitlin C, Park, S Lani, Madugundu, Guru, Patel, Yesha, Le Marchand, Loic, Stram, Daniel O, Tretyakova, Natalia
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2021
Matèries:
Cancer Biomarkers and Molecular Epidemiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8163050/
https://ncbi.nlm.nih.gov/pubmed/33693566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgab020
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