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Solid-phase fluorescent BODIPY–peptide synthesis via in situ dipyrrin construction

Traditional fluorescent peptide chemical syntheses hinge on the use of limited fluorescent/dye-taggable unnatural amino acids and entail multiple costly purifications. Here we describe a facile and efficient protocol for in situ construction of dipyrrins on the N-terminus with 20 natural and five un...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Wu, Yue, Tam, Wing-Sze, Chau, Ho-Fai, Kaur, Simranjeet, Thor, Waygen, Aik, Wei Shen, Chan, Wai-Lun, Zweckstetter, Markus, Wong, Ka-Leung
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8162834/
https://ncbi.nlm.nih.gov/pubmed/34094367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc04849f
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