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Heparin reversal by an oligoethylene glycol functionalized guanidinocalixarene

Unfractionated heparin (UFH), a naturally occurring anionic polysaccharide, is widely used as an anticoagulant agent in clinical practice. When overdosed or used in sensitive patients, UFH may cause various risks and a UFH neutralizer needs to be administered immediately to reverse heparinization. H...

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Vydáno v:Chem Sci
Hlavní autoři: Huang, Qiaoxian, Zhao, Hong, Shui, Mingju, Guo, Dong-Sheng, Wang, Ruibing
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society of Chemistry 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8162181/
https://ncbi.nlm.nih.gov/pubmed/34094229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc03922e
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