Chimeric HP-PRRSV2 containing an ORF2-6 consensus sequence induces antibodies with broadly neutralizing activity and confers cross protection against virulent NADC30-like isolate

Due to the substantial genetic diversity of porcine reproductive and respiratory syndrome virus (PRRSV), commercial PRRS vaccines fail to provide sufficient cross protection. Previous studies have confirmed the existence of PRRSV broadly neutralizing antibodies (bnAbs). However, bnAbs are rarely ind...

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Dades bibliogràfiques
Publicat a:Vet Res
Autors principals: Chen, Nanhua, Li, Shubin, Tian, Yunfei, Li, Xinshuai, Li, Shuai, Li, Jixiang, Qiu, Ming, Sun, Zhe, Xiao, Yanzhao, Yan, Xilin, Lin, Hong, Yu, Xiuling, Tian, Kegong, Shang, Shaobin, Zhu, Jianzhong
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8161975/
https://ncbi.nlm.nih.gov/pubmed/34044890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13567-021-00944-8
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