Integrin α5 promotes migration and invasion through the FAK/STAT3/AKT signaling pathway in icotinib-resistant non-small cell lung cancer cells

Patients with non-small cell lung cancer (NSCLC) treated with EGFR-tyrosine kinase inhibitors (TKIs) ultimately develop drug resistance and metastasis. Therefore, there is a need to identify the underlying mechanisms of resistance to EGFR-TKIs. In the present study, colony formation and MTT assays w...

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Pubblicato in:Oncol Lett
Autori principali: Yang, Yang, Wang, Yizhe, Che, Xiaofang, Hou, Kezuo, Wu, Jie, Zheng, Chunlei, Cheng, Yang, Liu, Yunpeng, Hu, Xuejun, Zhang, Jingdong
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2021
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8161469/
https://ncbi.nlm.nih.gov/pubmed/34084223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2021.12817
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