Regulatory Noncoding and Predicted Pathogenic Coding Variants of CCR5 Predispose to Severe COVID-19

Genome-wide association studies (GWAS) found locus 3p21.31 associated with severe COVID-19. CCR5 resides at the same locus and, given its known biological role in other infection diseases, we investigated if common noncoding and rare coding variants, affecting CCR5, can predispose to severe COVID-19...

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Publicado no:Int J Mol Sci
Main Authors: Cantalupo, Sueva, Lasorsa, Vito Alessandro, Russo, Roberta, Andolfo, Immacolata, D’Alterio, Giuseppe, Rosato, Barbara Eleni, Frisso, Giulia, Abete, Pasquale, Cassese, Gian Marco, Servillo, Giuseppe, Gentile, Ivan, Piscopo, Carmelo, Della Monica, Matteo, Fiorentino, Giuseppe, Russo, Giuseppe, Cerino, Pellegrino, Buonerba, Carlo, Pierri, Biancamaria, Zollo, Massimo, Iolascon, Achille, Capasso, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8161088/
https://ncbi.nlm.nih.gov/pubmed/34065289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22105372
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