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An Overview of the Relevance of IgG4 Antibodies in Allergic Disease with a Focus on Food Allergens

Antibodies of the IgG4 isotype are strongly associated with allergic disease but have several properties such as not precipitating with allergens, not activating complement and poor binding to Fcγ receptors that argue against a pro-inflammatory role. In keeping with that, IgG4 antibodies are a strik...

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Bibliografiske detaljer
Udgivet i:Children (Basel)
Main Authors: Platts-Mills, Thomas A. E., Keshavarz, Behnam, Wilson, Jeffrey M., Li, Rung-chi, Heymann, Peter W., Gold, Diane R., McGowan, Emily C., Erwin, Elizabeth A.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8160978/
https://ncbi.nlm.nih.gov/pubmed/34065166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/children8050418
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