The Role of IGF/IGF-IR-Signaling and Extracellular Matrix Effectors in Bone Sarcoma Pathogenesis

SIMPLE SUMMARY: Bone sarcomas are mesenchymal origin tumors. Bone sarcoma patients show a variable response or do not respond to chemotherapy. Notably, improving efficient chemotherapy approaches, dealing with chemoresistance, and preventing metastasis pose unmet challenges in sarcoma therapy. Insul...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cancers (Basel)
Auteurs principaux: Tzanakakis, George N., Giatagana, Eirini-Maria, Berdiaki, Aikaterini, Spyridaki, Ioanna, Hida, Kyoko, Neagu, Monica, Tsatsakis, Aristidis M., Nikitovic, Dragana
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Review
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8160938/
https://ncbi.nlm.nih.gov/pubmed/34069554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13102478
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