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Systemic Actions of SGLT2 Inhibition on Chronic mTOR Activation as a Shared Pathogenic Mechanism between Alzheimer’s Disease and Diabetes

Alzheimer’s disease (AD) affects tens of millions of people worldwide. Despite the advances in understanding the disease, there is an increased urgency for pharmacological approaches able of impacting its onset and progression. With a multifactorial nature, high incidence and prevalence in later yea...

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Vydáno v:Biomedicines
Hlavní autoři: Stanciu, Gabriela Dumitrita, Rusu, Razvan Nicolae, Bild, Veronica, Filipiuc, Leontina Elena, Tamba, Bogdan-Ionel, Ababei, Daniela Carmen
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8160780/
https://ncbi.nlm.nih.gov/pubmed/34069618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9050576
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