A Blood Bank Standardized Production of Human Platelet Lysate for Mesenchymal Stromal Cell Expansion: Proteomic Characterization and Biological Effects

Human platelet lysate (hPL) is considered a valid substitute to fetal bovine serum (FBS) in the expansion of mesenchymal stromal cells (MSC), and it is commonly produced starting from intermediate side products of whole blood donations. Through freeze–thaw cycles, hPL is highly enriched in chemokine...

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Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Bianchetti, Andrea, Chinello, Clizia, Guindani, Michele, Braga, Simona, Neva, Arabella, Verardi, Rosanna, Piovani, Giovanna, Pagani, Lisa, Lisignoli, Gina, Magni, Fulvio, Russo, Domenico, Almici, Camillo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8160451/
https://ncbi.nlm.nih.gov/pubmed/34055779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.650490
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