Monocyte-Derived Macrophages Contribute to Chitinase Dysregulation in Amyotrophic Lateral Sclerosis: A Pilot Study

Neuroinflammation significantly contributes to Amyotrophic Lateral Sclerosis (ALS) pathology. In lieu of this, reports of elevated chitinase levels in ALS are interesting, as they are established surrogate markers of a chronic inflammatory response. While post-mortem studies have indicated glial exp...

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Bibliografiske detaljer
Udgivet i:Front Neurol
Main Authors: Gaur, Nayana, Huss, Elena, Prell, Tino, Steinbach, Robert, Guerra, Joel, Srivastava, Akash, Witte, Otto W., Grosskreutz, Julian
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Neurology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8160083/
https://ncbi.nlm.nih.gov/pubmed/34054686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2021.629332
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