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Effects of Cholesterol on the Partitioning of a Drug Molecule in Lipid Bilayers

Drug molecules either bind to membrane-bound targets or permeate through cell membranes to reach intracellular targets, and hence their membrane partition and permeation are of great importance. Here we studied the effects of cholesterol on the partition of amantadine, an anti-flu drug molecule, int...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Yang, Yuqin, Dong, Hao, Zhou, Huan-Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159892/
https://ncbi.nlm.nih.gov/pubmed/33984232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.1c02436
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