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Mendelian randomisation for mediation analysis: current methods and challenges for implementation

Mediation analysis seeks to explain the pathway(s) through which an exposure affects an outcome. Traditional, non-instrumental variable methods for mediation analysis experience a number of methodological difficulties, including bias due to confounding between an exposure, mediator and outcome and m...

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Detaylı Bibliyografya
Yayımlandı:Eur J Epidemiol
Asıl Yazarlar: Carter, Alice R., Sanderson, Eleanor, Hammerton, Gemma, Richmond, Rebecca C., Davey Smith, George, Heron, Jon, Taylor, Amy E., Davies, Neil M., Howe, Laura D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Netherlands 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159796/
https://ncbi.nlm.nih.gov/pubmed/33961203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10654-021-00757-1
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