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Blocking Borrelia burgdorferi transmission from infected ticks to nonhuman primates with a human monoclonal antibody

Disrupting transmission of Borrelia burgdorferi sensu lato complex (B. burgdorferi) from infected ticks to humans is one strategy to prevent the significant morbidity from Lyme disease. We have previously shown that an anti-OspA human mAb, 2217, prevents transmission of B. burgdorferi from infected...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Schiller, Zachary A., Rudolph, Michael J., Toomey, Jacqueline R., Ejemel, Monir, LaRochelle, Alan, Davis, Simon A., Lambert, Havard S., Kern, Aurélie, Tardo, Amanda C., Souders, Colby A., Peterson, Eric, Cannon, Rebecca D., Ganesa, Chandrashekar, Fazio, Frank, Mantis, Nicholas J., Cavacini, Lisa A., Sullivan-Bolyai, John, Hu, Linden T., Embers, Monica E., Klempner, Mark S., Wang, Yang
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159683/
https://ncbi.nlm.nih.gov/pubmed/33914704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI144843
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