Blocking Borrelia burgdorferi transmission from infected ticks to nonhuman primates with a human monoclonal antibody

Disrupting transmission of Borrelia burgdorferi sensu lato complex (B. burgdorferi) from infected ticks to humans is one strategy to prevent the significant morbidity from Lyme disease. We have previously shown that an anti-OspA human mAb, 2217, prevents transmission of B. burgdorferi from infected...

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Библиографические подробности
Опубликовано в: :J Clin Invest
Главные авторы: Schiller, Zachary A., Rudolph, Michael J., Toomey, Jacqueline R., Ejemel, Monir, LaRochelle, Alan, Davis, Simon A., Lambert, Havard S., Kern, Aurélie, Tardo, Amanda C., Souders, Colby A., Peterson, Eric, Cannon, Rebecca D., Ganesa, Chandrashekar, Fazio, Frank, Mantis, Nicholas J., Cavacini, Lisa A., Sullivan-Bolyai, John, Hu, Linden T., Embers, Monica E., Klempner, Mark S., Wang, Yang
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2021
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159683/
https://ncbi.nlm.nih.gov/pubmed/33914704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI144843
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