HO-1/CO Maintains Intestinal Barrier Integrity through NF-κB/MLCK Pathway in Intestinal HO-1(−/−) Mice

BACKGROUND: Intestinal barrier injury is an important contributor to many diseases. We previously found that heme oxygenase-1 (HO-1) and carbon monoxide (CO) protect the intestinal barrier. This study is aimed at elucidating the molecular mechanisms of HO-1/CO in barrier loss. MATERIALS AND METHODS:...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Zhang, Zhenling, Zhang, Lijing, Zhang, Qiuping, Liu, Bojia, Li, Fang, Xin, Yi, Duan, Zhijun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159651/
https://ncbi.nlm.nih.gov/pubmed/34104309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6620873
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