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Large transition state stabilization from a weak hydrogen bond

A series of molecular rotors was designed to study and measure the rate accelerating effects of an intramolecular hydrogen bond. The rotors form a weak neutral O–H⋯O[double bond, length as m-dash]C hydrogen bond in the planar transition state (TS) of the bond rotation process. The rotational barrier...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Vik, Erik C., Li, Ping, Maier, Josef M., Madukwe, Daniel O., Rassolov, Vitaly A., Pellechia, Perry J., Masson, Eric, Shimizu, Ken D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159443/
https://ncbi.nlm.nih.gov/pubmed/34123031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc02806a
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